JPH0211568B2 - - Google Patents

Info

Publication number
JPH0211568B2
JPH0211568B2 JP57078893A JP7889382A JPH0211568B2 JP H0211568 B2 JPH0211568 B2 JP H0211568B2 JP 57078893 A JP57078893 A JP 57078893A JP 7889382 A JP7889382 A JP 7889382A JP H0211568 B2 JPH0211568 B2 JP H0211568B2
Authority
JP
Japan
Prior art keywords
ethyl acetate
ethyl
acid
compound
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP57078893A
Other languages
English (en)
Japanese (ja)
Other versions
JPS58194814A (ja
Inventor
Hiroaki Munakata
Makio Kobayashi
Kazuo Azuma
Shigeru Sato
Makoto Tsurufuji
Hiroshi Enomoto
Makoto Sugyama
Yoshihisa Shibata
Iwao Morita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Chemical Corp
Nippon Shinyaku Co Ltd
Original Assignee
Mitsubishi Kasei Corp
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp, Nippon Shinyaku Co Ltd filed Critical Mitsubishi Kasei Corp
Priority to JP57078893A priority Critical patent/JPS58194814A/ja
Priority to GB08311536A priority patent/GB2124077B/en
Priority to FR8307714A priority patent/FR2526659B1/fr
Priority to NL8301639A priority patent/NL8301639A/nl
Priority to SE8302694A priority patent/SE8302694L/
Priority to EP83104602A priority patent/EP0094599B1/en
Priority to DE8383104602T priority patent/DE3370585D1/de
Priority to AT83104602T priority patent/ATE26212T1/de
Priority to BE0/210741A priority patent/BE896712A/fr
Priority to CH2560/83A priority patent/CH656800A5/de
Priority to DE19833317107 priority patent/DE3317107A1/de
Priority to IT21018/83A priority patent/IT1200011B/it
Publication of JPS58194814A publication Critical patent/JPS58194814A/ja
Priority to US07/045,161 priority patent/US4720506A/en
Publication of JPH0211568B2 publication Critical patent/JPH0211568B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP57078893A 1982-05-11 1982-05-11 免疫調節作用を有する薬剤 Granted JPS58194814A (ja)

Priority Applications (13)

Application Number Priority Date Filing Date Title
JP57078893A JPS58194814A (ja) 1982-05-11 1982-05-11 免疫調節作用を有する薬剤
GB08311536A GB2124077B (en) 1982-05-11 1983-04-27 Immunomodulating agent
FR8307714A FR2526659B1 (fr) 1982-05-11 1983-05-09 Medicaments immunomodulants a base de derives de l'acide phenylacetique
NL8301639A NL8301639A (nl) 1982-05-11 1983-05-09 Immunomodulerend middel.
AT83104602T ATE26212T1 (de) 1982-05-11 1983-05-10 Verwendung von amino-phenylessigs ure-derivaten zur herstellung eines immunomodulatoren arzneimittels.
EP83104602A EP0094599B1 (en) 1982-05-11 1983-05-10 Use of aminophenylacetic acid derivatives for the manufacture of an immunomodulating medical preparation
DE8383104602T DE3370585D1 (en) 1982-05-11 1983-05-10 Use of aminophenylacetic acid derivatives for the manufacture of an immunomodulating medical preparation
SE8302694A SE8302694L (sv) 1982-05-11 1983-05-10 Immunomudulerande medel
BE0/210741A BE896712A (fr) 1982-05-11 1983-05-10 Medicaments immunomodulants a base de derives de l'acide phenylacetique.
CH2560/83A CH656800A5 (de) 1982-05-11 1983-05-10 Immunomodulierendes mittel.
DE19833317107 DE3317107A1 (de) 1982-05-11 1983-05-10 Immunomodulierendes mittel
IT21018/83A IT1200011B (it) 1982-05-11 1983-05-10 Agente immunomodulante
US07/045,161 US4720506A (en) 1982-05-11 1987-05-04 Immunomodulating agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57078893A JPS58194814A (ja) 1982-05-11 1982-05-11 免疫調節作用を有する薬剤

Publications (2)

Publication Number Publication Date
JPS58194814A JPS58194814A (ja) 1983-11-12
JPH0211568B2 true JPH0211568B2 (en]) 1990-03-14

Family

ID=13674488

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57078893A Granted JPS58194814A (ja) 1982-05-11 1982-05-11 免疫調節作用を有する薬剤

Country Status (12)

Country Link
US (1) US4720506A (en])
EP (1) EP0094599B1 (en])
JP (1) JPS58194814A (en])
AT (1) ATE26212T1 (en])
BE (1) BE896712A (en])
CH (1) CH656800A5 (en])
DE (2) DE3317107A1 (en])
FR (1) FR2526659B1 (en])
GB (1) GB2124077B (en])
IT (1) IT1200011B (en])
NL (1) NL8301639A (en])
SE (1) SE8302694L (en])

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8522186D0 (en) * 1985-09-06 1985-10-09 Erba Farmitalia Cycloalkyl-substituted 4-aminophenyl derivatives
US5605930A (en) * 1991-10-21 1997-02-25 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for treating and preventing pathologies including cancer
US6037376A (en) * 1991-10-21 2000-03-14 The United States Of America As Represented By The Department Of Health And Human Services Methods for therapy of cancer
US5635532A (en) * 1991-10-21 1997-06-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Compositions and methods for therapy and prevention of pathologies including cancer, AIDS and anemia
EP0604641B1 (en) * 1992-06-30 2002-03-20 SHAPIRO, Howard, K. Use of a combination containing an amine or amine-related derivative of benzoic acid and an amino-polysaccharide in the manufacture of a medicament for the treatment of inflammatory diseases
AU698881B2 (en) * 1994-05-11 1998-11-12 Howard K. Shapiro Compositions for treatment of chronic inflammatory diseases
WO1996018607A1 (en) * 1994-12-12 1996-06-20 Chugai Seiyaku Kabushiki Kaisha Aniline derivative having the effect of inhibiting nitrogen monoxide synthase
CA2495537C (en) * 2000-08-29 2010-03-30 Nobex Corporation Immunoregulatory compounds and derivatives and methods of treating diseases therewith
GB0113366D0 (en) * 2001-06-01 2001-07-25 Ks Biomedix Ltd Composition
US8048924B2 (en) 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
ITMI20012434A1 (it) * 2001-11-20 2003-05-20 Dompe Spa Acidi 2-aril-propionici e composizioni farmaceutiche che li contengono
RU2228175C1 (ru) * 2002-12-10 2004-05-10 Лимонов Виктор Львович Иммуностимулятор
RU2245142C1 (ru) * 2003-07-14 2005-01-27 Лимонов Виктор Львович Иммуномодулятор
RU2253445C1 (ru) * 2003-12-02 2005-06-10 Лимонов Виктор Львович Иммуномодулятор
RU2253447C1 (ru) * 2003-12-08 2005-06-10 Лимонов Виктор Львович Иммуномодулятор
WO2005084658A1 (en) * 2004-03-04 2005-09-15 Arakis Ltd. Derivatives of actarit and their therapeutic use
WO2006014549A2 (en) 2004-07-07 2006-02-09 Nobex Corporation Synthesis of azo bonded immunoregulatory compounds
GB0423927D0 (en) * 2004-10-27 2004-12-01 Arakis Ltd The treatment of IBD
ITRM20050389A1 (it) 2005-07-22 2007-01-23 Giuliani Spa Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.
UA107562C2 (uk) 2008-12-05 2015-01-26 Спосіб лікування псоріазу
MX381002B (es) 2009-02-16 2025-03-12 Nogra Pharma Ltd Compuestos de alquilamido y usos de los mismos.
AU2013217933B2 (en) 2012-02-09 2017-11-30 Nogra Pharma Limited Methods of treating fibrosis
BR112014026160A2 (pt) 2012-04-18 2017-07-18 Nogra Pharma Ltd métodos para tratar intolerância à lactose
CN106278925B (zh) * 2016-08-08 2019-01-25 平光制药股份有限公司 一种对乙酰氨基苯乙酸的制备方法
CA3128302A1 (en) 2019-02-08 2020-08-13 Nogra Pharma Limited Process of making 3-(4'-aminophenyl)-2-methoxypropionic acid, and analogs and intermediates thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL133740C (en]) * 1965-04-08
GB1082466A (en) * 1965-06-29 1967-09-06 Smith & Nephew 2-benzamidophenylalkanoic acid derivatives and their preparation
DE2034240C2 (de) * 1968-03-27 1982-12-02 CIBA-GEIGY AG, 4002 Basel Isoindolinderivate, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung
US3641040A (en) * 1968-03-27 1972-02-08 Ciba Geigy Corp Tertiary amino phenyl acetic acids
DE1913742A1 (de) * 1968-03-27 1969-10-09 Ciba Geigy Tertiaere aliphatische Aminosaeuren
FR2193579A2 (en) * 1972-07-25 1974-02-22 Bouchara Emile Para amino phenyl acetic acids - analgesics and antiinflammatories, prepd. by alkylation of prim amino acid
US3997669A (en) * 1972-12-26 1976-12-14 Ciba-Geigy Corporation Tertiary aminoacids
JPS5572167A (en) * 1978-11-27 1980-05-30 Dainippon Pharmaceut Co Ltd Pyridylaminophenylacetic acid derivative and its preparation

Also Published As

Publication number Publication date
SE8302694D0 (sv) 1983-05-10
JPS58194814A (ja) 1983-11-12
EP0094599B1 (en) 1987-04-01
DE3370585D1 (en) 1987-05-07
EP0094599A1 (en) 1983-11-23
ATE26212T1 (de) 1987-04-15
GB2124077A (en) 1984-02-15
BE896712A (fr) 1983-11-10
CH656800A5 (de) 1986-07-31
FR2526659B1 (fr) 1986-07-04
SE8302694L (sv) 1983-11-12
GB2124077B (en) 1986-12-03
NL8301639A (nl) 1983-12-01
DE3317107A1 (de) 1983-11-24
US4720506A (en) 1988-01-19
GB8311536D0 (en) 1983-06-02
IT1200011B (it) 1989-01-05
IT8321018A0 (it) 1983-05-10
FR2526659A1 (fr) 1983-11-18

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Legal Events

Date Code Title Description
EXPY Cancellation because of completion of term